Estimating the reliability of glycemic index values and potential sources of methodological and biological variability.

Nirupa R Matthan, Lynne M Ausman, Huicui Meng, Hocine Tighiouart, and Alice H Lichtenstein

Background: The utility of glycemic index (GI) values for chronic disease risk management remains controversial. Although absolute GI value determinations for individual foods have been shown to vary significantly in individuals with diabetes, there is a dearth of data on the reliability of GI value determinations and potential sources of variability among healthy adults.
Objective: We examined the intra- and inter-individual variability in glycemic response to a single food challenge and methodologic and biological factors that potentially mediate this response. READ MORE>